Science Journal of Medicine and Clinical Trials
November 2012,Volume 2012, ISSN: 2276-7487
© Author(s) 2012. This work is distributed under the Creative Commons Attribution 3.0 License.
Research Article
Evaluation of Serum Antioxidant Vitamin Levels in Term And Preterm Neonates and Their Mothers
Mahmoud Ebrahim Al Rashedy1,YaserA.Ahmed2, Ahmed Elsayed Hammour2*
Amira M. M.Hamed2, Abbas ElbakryA.Elsayed2, Alaa M. Hashim3, Mohammad M. Abolfotouh4
Obstetrics and Gynecology1, Pediatric2, clinical pathology 3 and Medical Biochemistry Department4,Faculty of Medicine. Al-AzharUniversity. (Assiut & Cairo*) Egypt.
Accepted 6 September, 2012; Available Online 7 November, 2012.
doi: 10.7237/sjmct/142
Abstract:
Background: Antioxidant vitamins such as vitamins A, C and E
may play a role in fetal growth Objectives:to determine and
correlate serum levels of antioxidant vitamins (A, C and E) in term
and preterm newborns and their mothers.
Materials and methods: Thirty apparently healthy neonates were
classified into 15 full term and 15 preterm neonates along with
their mothers. Blood samples were collected from all neonates and
their mothers for the estimation of serum antioxidant vitamins A,
C and E.
Results:The mean levels of serum vitamins A & E were significantly
lower in neonatal than in maternal sera while the level of vitamin
C was significantly higher in neonatal than in maternal sera. At the
same time the levels of these vitamins were significantly lower in
preterm compared to term neonates. A significant positive
correlations were found between neonatal and maternal serum
vitamin A&E levels, whereas Vit c showed no significant
correlations.
Conclusions: Antioxidant vitamins appear to accumulate during
the third trimester, so preterm infants are more susceptible to
oxidative stress.
Keyword: antioxidant vitamins, pregnancy, oxidative stress, term and preterm neonates.