The adequate handling of missing data in medical research still constitutes a major problem of statistical data analysis. Although different imputation strategies and methods have been developed in recent years, none of them can be used unhesitatingly in arbitrary missing data situations. A commonly observed drawback of the established imputation methods is their sensitivity against the number of missing values in the analysis set, the underlying missing data mechanism and scale level of the incomplete variable. The extent of this sensitivity is indeed different for individual methods. A novel approach for the imputation of missing data was proposed here which especially does not depend on the scale level of the variable that is affected by missing values. This approach in a multiple imputation setting was based on the calculation of propensity scores and their usage in creating adequate imputation values, resting upon a Hot Deck principle. In the course of a real-data based simulation study, the proposed method was compared to a standard multiple imputation approach and a complete case analysis strategy. The results showed that there was a dependency of imputation's goodness from the assumed missing data proportion, too. However, the developed imputation method generated consistent estimations of the width of confidence intervals and could be applied for different kinds of incomplete variables straightforwardly, which is not possible with other imputation approaches that easily in general..

Keyword:Hot deck imputation; Missing values; Multiple Imputation; Propensity Score.

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